Methyl 2-Acetylamino-3-Chloropropionate CAS 18635-38-6 Ramipril Intermediate Purity ≥99.0% (HPLC)
Ruifu Chemical is the leading manufacturer of Methyl 2-Acetylamino-3-Chloropropionate (CAS: 18635-38-6) with high quality, intermediate of Ramipril (CAS 87333-19-5). Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Methyl 2-Acetylamino-3-Chloropropionate, Please contact: alvin@ruifuchem.com
| Chemical Name | Methyl 2-Acetylamino-3-Chloropropionate |
| Synonyms | L-N-Acetyl-β-Chloroalanine Methyl Ester; Methyl (R)-2-Acetamido-3-Chloropropanoate; N-Acetylmine-3-Chloro-L-Alaninemethyl Ester; Methyl N-Acetyl-3-Chloro-L-Alaninate; Methyl N-Acetyl-3-Chloroalaninate; Ac-DL-Ala(Cl)-OMe |
| Stock Status | In Stock, Commercial Production |
| CAS Number | 18635-38-6 |
| Molecular Formula | C6H10ClNO3 |
| Molecular Weight | 179.60 g/mol |
| Melting Point | 102.0~105.0℃ |
| COA & MSDS | Available |
| Origin | Shanghai, China |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Appearance | White to Off-White Powder | Complies |
| Melting Point | 102.0~105.0℃ | 102.0~105.0℃ |
| Loss on Drying | ≤0.50% | 0.26% |
| Specific Rotation | -13.0° to -16.0° | -13.15° |
| Purity / Analysis Method | ≥99.0% (HPLC) | 99.27% |
| Infrared Spectrum | Consistent with Structure | Complies |
| 1H NMR Spectrum | Consistent with Structure | Complies |
| Conclusion | The product has been tested and complies with the given specifications | |
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Methyl 2-Acetylamino-3-Chloropropionate (CAS: 18635-38-6), intermediate of Ramipril (CAS 87333-19-5). Ramiprilat is the active metabolite of ramipril and functions as an angiotensin-converting enzyme inhibitor (pKi = 9.08 in human heart) to suppress the conversion of angiotensin I to angiotensin II and the degradation of bradykinin, thereby preventing vasoconstriction. Furthermore, ramiprilat is reported to interfere with the targeting of B2 kinin receptors to endothelial cell membranes further preventing bradykinin signaling. In addition to its cardioprotective effects in both animal models and clinical studies, ramiprilat has been reported to inhibit matrix metalloproteinase-3 and -9 activity in isolated Crohn’s disease fistulas.
